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Index > Protein center > F12(Gene name) > Bovine
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  • F12 (Gene name),
  • Coagulation factor XII (Protein name ),  FA12_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    F12;
    Protein name:
    Coagulation factor XII;
    Alternative:
    Hageman factor(HAF);
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Interacts with HRG; the interaction, which is enhanced in the presence of zinc ions and inhibited by heparin-binding, inhibits factor XII autoactivation and contact-initiated coagulation.
    Function:
    Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    612
    Sequence:
    50:
    MRALLLLGAL | LVSLESTVST | PPWKGPKKHK | LTDSEHTVVL | TVTGEPCHFP | 
    100:
    FQYHRQLHHK | CIHRGRPGPR | PWCATTPNFE | KDQRWAYCLE | PKKVKDHCSK | 
    150:
    HNPCQKGGTC | VNMPDGPRCI | CADHFTGKHC | QKEKCFEPQF | FRFFHENEIW | 
    200:
    HRLEPAGVVK | CQCKGPNAQC | KPLASQVCRT | NPCLNGGSCL | QAEGHRLCRC | 
    250:
    APSFAGRLCD | VDLKASCYDD | RDRGLSYRGM | AGTTLSGAPC | QSWASEATYW | 
    300:
    NVTAEQVLNW | GLGDHAFCRA | STPPRGYRNP | DNDTRPLCFI | WKGDRLSWNY | 
    350:
    CRLAPCQAAA | GHEHFPLPSP | SALQKPESTT | QTPLPSLTSG | WCSPTPLASG | 
    400:
    GPGGCGQRLR | KWLSSLNRVV | GGLVALPGAH | PYIAALYWDQ | HFCAGSLIAP | 
    450:
    CWVLTAAHCL | QNRPAPKELT | VVLGQDRHNQ | SCEQCQTLAV | RDYRLHEAFS | 
    500:
    PITYQHDLAL | VRLQESADGC | CAHPSPFVQP | VCLPSTAARP | AESEAAVCEV | 
    550:
    AGWGHQFEGG | EYSSFLQEAQ | VPLIDPQRCS | APDVHGAAFT | QGMLCAGFLE | 
    600:
    GGTDACQGDS | GGPLVCEDET | PERQLILRGI | VSWGSGCGNR | LKPGVYTDVA | 
    612:
    NYLAWIREHT | AS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Coagulation factor XII
    Cat.:
    E0694h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Bovine Coagulation factor XII
    Cat.:
    E0694p
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Bovine Coagulation factor XII
    Cat.:
    E0694b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Bovine Coagulation factor XII
    Cat.:
    E0694r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Bovine Coagulation factor XII
    Cat.:
    E0694m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    CLIA Kit for Bovine Coagulation factor XII
    Cat.:
    U0694b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Coagulation factor XII
    Cat.:
    U0694r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Coagulation factor XII
    Cat.:
    U0694m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Coagulation factor XII
    Cat.:
    U0694h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Coagulation factor XII
    Cat.:
    U0694p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine Coagulation factor XII
    Cat.:
    P0694Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Coagulation factor XII
    Cat.:
    P0694Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Coagulation factor XII
    Polyclonal Antibody for Bovine Coagulation factor XII
    Cat.:
    P0694Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Coagulation factor XII
    Monoclonal Antibody for Bovine Coagulation factor XII
    Monoclonal Antibody for Bovine Coagulation factor XII
    Monoclonal Antibody for Bovine Coagulation factor XII
    Monoclonal Antibody for Bovine Coagulation factor XII
    Monoclonal Antibody for Bovine Coagulation factor XII
    Protein for Bovine Coagulation factor XII
    Protein for Bovine Coagulation factor XII
    Protein for Bovine Coagulation factor XII
    Protein for Bovine Coagulation factor XII
    Protein for Bovine Coagulation factor XII

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    Precision
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    Linearity
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    References
    1. 1.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2006-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Fetal liver.
    2. 2.
      "Primary structure of bovine Hageman factor (blood coagulation factor XII): comparison with human and guinea pig molecules."
      Shibuya Y. , Semba U. , Okabe H. , Kambara T. , Yamamoto T.
      Biochim. Biophys. Acta1206:63-70(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 11-612
      tissue: Liver.
    3. 3.
      "Isolation and characterization of bovine factor XII (Hageman factor)."
      Fujikawa K. , Walsh A.K. , Davie W.E.
      Biochemistry16:2270-2278(1977) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 20-31; 369-383 AND 544-569
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